Biological membranes are a fascinating medium, participating in virtually every biological process. We are interested in interactions of multiple proteins and nanoobjects with model cell systems, and subsequent membrane-mediated phenomena.
Thus far we have shown how viruses or nanoparticles can self-assemble into a variety of beautiful and functional patterns when adhering to biological membranes. Furthermore, we found that these particles can induce long tubular protrusions in the membrane, which is a novel route for entry into cell membranes, and points to an unexplored pathway of viral infection.
- M. Šimunović, A. Šarić, M. Henderson, K. Y. C. Lee and G. A. Voth, Lipid membrane mediates long-range interactions between linear aggregates of membrane-curving proteins, Submitted (2016).
- C. van der Wel, A. Vahid, A. Šarić, T. Idema, D. Heinrich and D. J. Kraft, Lipid membrane-mediated attraction between curvature inducing object, Scientific Reports 6, 32825 (2016).
- S. J. Bachmann, J. Kotar, L. Parolini, A. Šarić, P. Cicuta, L. Di Michele and B. M. Mognetti, Melting transition in lipid vesicles functionalised by mobile DNA linkers, Soft Matter 12, 7804 (2016).
- A. Šarić and A. Cacciuto. Self-assembly of nanoparticles adsorbed on fluid and elastic membranes. Soft Matter 9, 6677 (2013). (Review article.)
- A. Šarić and A. Cacciuto. Mechanism of membrane tube formation induced by adhering nanocomponents. Phys. Rev. Lett. 109, 188101 (2012). (Cover paper of the weekly issue. Highlighted in Physics Synopsis.)
- A. Šarić and A. Cacciuto. Fluid membranes can drive linear aggregation of adsorbed spherical nanoparticles. Phys. Rev. Lett. 108, 118101 (2012). (Editor’s suggestion.)